Oriental College of Pharmacy is committed to excellence and expanded opportunities for our students. With experienced faculty and staff and modern infrastructure, O.C.P. is prepared to provide its students state-of-the-art education with opportunities found like nowhere else in the country. At O.C.P., we strive to improve our ability to provide excellence in pharmaceutical care and education by strengthening our ability to act strategically in relation to the rapid and dynamic changes in the profession

State-of-the art fifteen laboratories help students to practically learn the theoretical concepts and also gives hands on training on sophisticated instruments.
The college is equipped with all the essential instruments (including sophisticated instruments such as UV-Vis spectrophotometer, FTIR, HPLC, Lyophilizer, Spray dryer, deep freezer, theromstability chamber etc) as desired by various regulatory bodies including University of Mumbai.
Each laboratory is provided with firefighting equipment, emergency shower and first-aid box for safety.
State-of-the-art, Committee for the Purpose of Control & Supervision of Experimentation on Animals (CPCSEA) approved fully air conditioned animal house facility to conduct experiments using various animals like Mice, Rats, Guinea Pig, Rabbits.

Research Expertise

Area of Research Expertise: CRDDS, NDDS, Topical dosage forms, Nanotechnology

Research Projects Handled:

Minor Research Project of Mumbai University

  1. Design and Evaluation of Castor oil based Anti-inflammatory Emulgel for Arthritis
  2. Solubility enhancement of poorly soluble drugs by employing solid dispersion technique

Guided Research project of M. Pharm. Students

  1. Formulation and development of NDDS using cyclodextrin
  2. Formulation and characterization of liposomes
  3. Formulation and characterization of liposomes
  4. Evaluation of controlled drug delivery systems
  5. Preparation and study of novel drug delivery system
  6. Preparation and evaluation of oral dosage formulation
  7. Studies in development of controlled drug delivery system
  8. Formulation and evaluation of controlled drug delivery system
  9. Formulation, development and evaluation of NDDS
  10. Design and development of oral drug formulation
  11. Optimization and evaluation of pharmaceutical dosage forms
  12. Design and development of drug delivery systems
  13. Design and development of novel drug delivery system
  14. Design, optimization and testing of oral delivery system
  15. Formulation and optimization of oral drug delivery system
  16. Formulation and development of novel drug delivery system
  17. Preparation and characterization of oral controlled drug delivery system
  18. Development and evaluation of novel drug delivery system
  19. Design and characterisation of dosage forms
  20. Preparation and evaluation of oral drug delivery system
  21. Formulation and evaluation of delivery systems

 

Research Publications:

  1. Sudha Rathod, Rasika K, Asish D,International Journal of Pharmacy and Pharmaceutical Sciences , “In Vitro released and in vivo tissue localization of 5-fluro Uracil loaded Microspheres” , International Journal of Pharmacy and Pharmaceutical Sciences, Vol 6 ,issue 1, 2014, ISSN- 0975-1491.
  2. Asmita Singh ,Sudha Rathod, International Journal of Pharm.Sciences and Research(IJPSR), “Design, Development and Characterization of Liposomal Neem Gel”, Vol 5 ,Issue.04 Apr 2014, ISSN:0975-9492.
  3. Rathod S.,Surve GD,Phansekar M, Bhagwan A, IJPRS , “A Review on Mouth Dissolving Film Technology”, Vol-3 I-1, 2014, ISSN No. 2277-7873.
  4. Sudha Rathod, Vishakha Kulkarni .IJAPR “Development and evaluation of curcumin Liposomal Gel” April 2013. Vol.4/ Issue 4, 1635-1639
  5. Sudha Rathod, Sadaf Momin .IJAPR “Development validation and stability study for simultaneous estimation of metformin and sitagliptin by hplc in bulk and marketed formulation”. May 2013 Vol.4/ Issue 4, 796-1802
  6. Sudha Rathod, S.G. Deshpande. “Patient Compliant ophthalmic Dosage form of Gatifloxacin”. IJPTR, Sept 2012, Vol 4, No. 3, ISSN 0974- 4304.
  7. Sudha Rathod, Vishakha Kulkarni, “Natural Polymers-A Comprehensive Review”. IJRPBS, Dec 2012, Vol.3, ISSN 2229-3701.
  8. Sudha Rathod, S.G. Deshpande. “Design and evaluation of Liposomic formulation of pilocarpine nitrate” Indian Journal of Pharm. Sci. March – April 2010, 72(2) : 155- 160.
  9. Sudha Rathod, S.G. Deshpande. “Bioavailability studies of ocular gels of Pilocarpine micropheres.” International Journal of Pharm. Tech Research, April – June 2010, 0974-4304Vol. 2, No2. PP 1022-1029.
  10. Sudha Rathod, S.G. Deshpande. “Design and Evaluation of Drug Loaded Erythrocytes.” International Journal of Pharm. Tech Research, April – June 2010, 0974-4304. Vol.2, No.2, PP 1550 – 1557.
  11. Sudha Rathod and S.G. Deshpande. Albumin microspheres as an ocular Delivery systemfor pilocarpine nitrate, Indian Journal of Pharm. Sci. Vol. 70, Issue (2) PP 193-197 March– April 2008.

 

Books Published:

Patents:

  1. Indian patent (MUM/2384/2014): Castor oil emulgel

Area of Research Expertise: Mucoadhesive drug delivery system

Research Projects Handled: Mumbai University’s minor research Project “Formulation Development and Pharmacotechnical Evaluation of Mucoadhesive drug delivery system for oral candidiasis”

Research Publications:

  • Pooja Abang, Munira Momin,.Mayur Inamdar and Swapan Kar. Transmucosal Drug Delivery – An Overview. Drug Delivery Letters, Volume 3(2), 2013
  • Munira Momin, K. Pundarikakshuhdu, S. K. Kar, Pharmacotechnical evaluation and optimization of compression coated colon specific drug delivery system containing Embeline, Journal of Pharmacy Research, 5(6), 3494-3499, 2012
  • Munira Momin, S.K.Kar et.al, Taste Masking techniques for bitter drugs- an overview, International Journal of Pharm Tech, July-2012, Vol. 4, Issue No.2, 2100-2118
  • Kishor Butte, Munira Momin, Suvarna Kurhade and Swapan Kumar Kar, Intravescal drug delivery system for bladder-An overview, International Journal of Pharmaceutical, Chemical and Biological Sciences, IJPCBS 2013, 3(3), 680-691, Issue No. 2249-9504.
  • S. K. Kar, Munira Momin, Sonali Joshi, Chaitrali Kute and Aarti Jaybhaye Published 01 March, 2015.Formulation development and pharmacotechnical evaluation of mucoadhesive drug delivery system for oral candidiasis (Research Article).International Journal of Pharmaceutical Sciences and Research. Kar et al., IJPSR, 2015; Vol. 6(3): 1156-1160. E-ISSN: 0975-8232; P-ISSN: 2320-5148, Published on 01 March 2015.

Patents: Nil

Area of Research Expertise: Novel drug delivery system, controlled drug delivery system.

Research Projects Handled:

Minor Research Project of Mumbai University

  1. Formulation and evaluation of micro sponge dosage forms
  2. Formulation and Evaluation of Triphala Effervescent Granules

Guided Research project of M. Pharm. Students

  1. Design and evaluation of oral drug delivery system
  2. Formulation and evaluation of oral drug delivery system
  3. Studies and formulation of oral drug delivery system
  4. Formulation and optimization of oral drug delivery system
  5. Design, development and evaluation of ocular drug delivery system
  6. Formulation and evaluation of dosage forms
  7. Design development and evaluation of oral drug delivery systems.
  8. Formulation and evaluation of controlled drug delivery system
  9. Formulation and Characterisation of drug delivery systems.
  10. Formulation and evaluation of oral drug delivery system
  11. Formulation and characterization of oral drug delivery system
  12. Development and evaluation of oral solid dosage form
  13. Design and evaluation of pharmaceutical dosage from
  14. Formulation and development of oral drug delivery system and its evaluation
  15. Development and evaluation of oral drug delivery systems.
  16. Formulation & evaluation of sustained release dosage from
  17. Formulation design and development of controlled drug delivery system

Research Publications:

  1. A.Dev, R. Chodankar, O. Shelke, “Emulgels: a novel topical drug delivery system,” Pharmaceutical and Biological Evaluations, vol.2, no.4, pp.64-75, 2015. [ISSN: 2394-0859]
  2. A.Dev, “Current aspects in ocular polymeric in-situ gelling system,” European Journal of Biomedical AND Pharmaceutical sciences,vol 3,no.4,March 2016.[2349-8870]
  3. A.Dev, Ganesh Deshmukh “Current approaches in buccal drug delivery system”Pharmaceutical and Biological Evaluations, vol.3, no.2, March, 2016. [ISSN: 2394-0859]
  4. A.Dev, Ganesh Deshmukh, “An overview of in situ gelling systems,” Pharmaceutical and Biological Evaluations, vol.3, no.1, March, 2016. [ISSN: 2394-0859]
  5. A.Dev, “Critical aspects in sublingual route of drug delivery,”Pharmaceutical and Biological Evaluations, vol.3, no.1, March, 2016. [ISSN: 2394-0859]
  6. A.Dev, “Comprehensive review on orally disintegrating dosage forms,”European Journal of Biomedical AND Pharmaceutical sciences,vol 3,no.3,April 2016.[2349-8870]
  7. Sudha Rathod, Rasika K, Asish D,International Journal of Pharmacy and Pharmaceutical Sciences , “In Vitro released and in vivo tissue localization of 5-fluro Uracil loaded Microspheres” , International Journal of Pharmacy and Pharmaceutical Sciences, Vol 6 ,issue 1, 2014, ISSN- 0975-1491
  8. Manoranjan Sahu, Smitapadma Mohanty, Asish Dev,International Journal of Pharmacy and Analytical Research. “A review on mouth dissolving tablets”, Issue 1, Vol- 4, Jan-Mar 2015, ISSN: 2320-2831.

Patents: Nil

Area of Research Expertise: GRDDS, Colon Targeting, Ophthalmic Drug Delivery, NDDS.

Research Projects Handled:

Minor Research Project of Mumbai University

  1. Formulation Development and In-Vitro Evaluation of Amoxicillin Trihydrate Mucoadhesive Film.
  2. Preparation and evaluation of cationic cyclosporine microspheric gel

Guided Research project of M. Pharm. Students

  1. Design and evalution of novel drug delivery system.
  2. Development and evaluation of oral drug delivery system
  3. Formulation and evalution of oral drug delivery system
  4. Formulation and characterization of pharmaceutical dosage form.
  5. Development and characterization of pharmaceutical dosage form.
  6. Design formulation and evalution of pharmaceutical dosage form.
  7. Formulation and evalution of oral dosage form.
  8. Formulation and optimization of oral drug delivery system.
  9. Formulation and characterization of Novel Drug Delivery System.
  10. Formulation and development of topical drug delivery system.
  11. Formulation and characterisation of tablet dosage form.
  12. Formulation and evaluation of solid dosage form.
  13. Design, Development and Evaluation of Drug Delivery System.
  14. Formulation and development of novel drug devilry system

Research Publications:

  1. Orodispersible Tablets: A Comprehensive Review, Research Journal of Pharmacy and Technology Year : 2014, Volume : 7, Issue : 3 First page : ( 368) Last page : ( 375) Print ISSN : 0974-3618. Online ISSN: 0974-360X.
  2. An overview of in situ gelling systems, Pharmaceutical and Biological Evaluations,Vol 3, No 1 (2016).
  3. Bilayer Technology: Novel Approach. Research Journal of Pharmacy and Technology, Volume 6 Issue 12 Pages 1443-1451
  4. Current approaches in buccal drug delivery system, Pharmaceutical and Biological Evaluations, Volume 3 Issue 2 Pages 165-177
  5. Stability Studies of Garcinia indica by Determination of Anthocyanins, Research Journal of Pharmacognosy and Phytochemistry Volume 2 Issue 2 Pages 144-147
  6. Patient Compliant Ophthalmic Dosage form of Gatifloxacin, International Journal of PharmTech Research CODEN (USA): IJPRIF ISSN : 0974-4304 Vol.4, No.3, pp 1033-1040, July-Sept 2012.

Area of Research Expertise: Novel drug delivery systems (NDDS), Liver cancer, Oral drug delivery systems, Nanotechnology

Research Projects Handled:

5 Projects handled:

  1. Completed the project “Novel carriers for Treatment of Hepatic Cancer” as a part of Ph.D research work
  2. ‘Novel drug delivery systems’ under the guidance of Dr. Sajeev Chandran as a part of M.Pharm project in Lupin research park, Pune
  3. ‘Aloe vera based Cosmeceuticals’ under the guidance of Dr. Archana Roy completed in November 2008
  4. Theoretical project on ‘Mechanisms of Nociception’ under the guidance of Dr. Vaigunda Ragavendran as a part of the course: Professional practice-І from January to April 2008
  5. Completed the project ‘Transgenic plants’ under the guidance of Dr. Sandhya Parmeshwaran in 2006

Research Publications:

International (9):

  1. Darshana Jain, Rajani Athawale, Amrita Bajaj, Shruti Shrikhande, Abhijeet Pandey, Peeyush Goel, Satish Patil, Preeti Raut. Thermosensitive PLA Based Nanodispersion for Targeting Brain Tumor via Intranasal Route. Accepted for publication in Materials Science and Engineering C.
  2. Shruti Shrikhande, Darshana Jain, Rajani Athawale, Amrita Bajaj. Nanoparticulate drug delivery systems for the Treatment of Hepatocellular Carcinoma. Current Cancer therapy Reviews. Bentham Publications, 2014; 10, 22-33.
  3. Shruti Shrikhande, Darshana Jain, Rajani Athawale, Amrita Bajaj, Peeyush Goel, Yuvraj Nikam, Rajiv Gude, Zahid Kamran. Evaluation of antimetastatic potential of Cisplatin polymeric nanocarriers on B16F10 melanoma cells, Saudi Pharmaceutical Journal, Elsevier Publications, 2015
  4. Darshana Jain, Rajani Athawale, Amrita Bajaj, Shruti Shrikhande. Double- Salting out assisted liquid-liquid extraction (SALLE) HPLC method for estimation of Temozolomide from biological samples. Journal of Chromatography B. Accepted for publication
  5. Darshana Jain, Rajani Athawale, Amrita Bajaj, Shruti Shrikhande. Surface coated PA nanoparticles loaded with Temozolamide for improved brain deposition and potential treatment of gliomas: Development, Characterization and In-vivo studies. Accepted for publication in Drug delivery, Informa Healthcare.
  6. K Amrita Rao, Shruti Shrikhande, Amrita Bajaj. Development of Cisplatin Nanoparticles as Dry Powder Inhalers for Lung Cancer. Current Nanoscience. 2012; Volume 8, Issue 6. Bentham Publications
  7. Nilakshi Nerkar, Amrita Bajaj, Shruti Shrikhande, Darshana Jain. Formulation of lipospheres for paclitaxel and assessment of in-vitro cytotoxicity against U373 cell line. Thai Journal of Pharmaceutical Sciences. 2012; 36(3): 117-130
  8. Darshana Jain, Rajani Athawale, Amrita Bajaj, Shruti Shrikhande, Peeyush N. Goel, Rajiv P. Gude. Studies on stabilization mechanism and stealth effect of poloxamer 188 onto PLGA nanoparticles. Colloids and Surfaces B: Biointerfaces, 2013, 109, 59-67
  9. Darshana Jain, Rajani Athawale, Amrita Bajaj, Shruti Shrikhande, Peeyush Goel, Yuvraj Nikam, R.P Gude. Poly lactic acid (PLA) nanoparticles sustain the cytotoxic action of temozolomide in C6 Glioma cells. Biomedicine & Aging Pathology, 2013

National (4):

  1. Shruti Shrikhande, Darshana Jain, Rajani Athawale, Amrita Bajaj. Development and validation of a U.V colorimetric method for estimation of Cisplatin in Pharmaceutical formulations. Indian Drugs, 2014, 51(7): 23-30.
  2. S. S. Shrikhande, A. Bajaj, B. Pinto. Rifampicin and Isoniazid Microcapsules for Treatment of Tuberculosis. International Journal of Pharmaceutical Sciences and Research; 2012; Volume 3, Issue 1
  3. S. S. Shrikhandea, A. Rao, A. Ambekar, A. N. Bajaj, Metered Dose Inhalation Formulations of Salbutamol Sulphate Using Non-CFC Propellant Tetrafluoroethane. International Journal of Pharmaceutical Sciences and Drug Research 2011; 3(4): 292-296
  4. Amrita K, Pullam Raju K, Shrikhande S, Prudhvi R P, Biswas U. K, Bajaj A. Technology Transfer: A New Buzz Word in Pharmaceutical Industry. Journal of Advanced Scientific Research, 2013, 4(1): 01-06

Patents:

1 provisional patent: Pharmaceutical compositions of polymeric nanoparticles. Provisional patent application number: 2529/MUM/2014.

Area of Research Expertise: Extraction, Isolation, Identification and Characterization of Natural Products

Research Projects Handled:

Minor Research Project of Mumbai University

  • Isolation of essential oil from culinary drugs and screening for their anti depressant potential

Minor Research Project of sponsored by OES

  • Isolation of essential oil from Lauraceous leaves and Shiff’s reaction based derivatisation of cinnamaldehyde.

Guiding Research Project of Ph. D. Students

  1. Bioactivity directed isolation and pharmacological and analytical profile of Derris brevibes
  2. Bioactivity guided fractionation of phytoconstituents in Woodfordia fruiticosa for Antiulcer Potential
  3. Phytochemical and pharmacological screening of selected medicinal plant available in Nizambad district
  4. Comparative phytopharmacology of leaves of Ficus species
  5. Design and optimization of fast disintegrating tablets for antiemetic drugs using natural super disintegrants
  6. Comparative pharmacognostical, phytochemical and neuropharmacological profile of plants Swertia chiratya and Hemidesmus indicus
  7. Isolation of Reserpine from Rauwolfia Species, its derivatization and Pharmacological Evaluation of Analogues
  8. Phytochemical and pharmacological investigations on Ficus dalhausiae MIQ

Publications for 2015

  1. International Journal of Pharmaceutical Sciences and Research Isolation, Purification and Structural Elucidation of Flavonoids from Methanol Extract of Ariel Parts of Derris Breviceps (Benth.) Baker Vol. 6(1): 2015; 491-501. ISSN: 2320-5148
  2. Asian Journal of Pharmaceutical and Clinical Research Anti-inflammatory Activity of Ficus Dalhousiae MIQ Roots of Ethanolic Extract in Wistar Albino Rats Vol 8, Issue 1, 2015, ISSN – 0974-2441
  3. Research Journal of Pharmacognosy and Phytochemistry Preliminary Phytochemical Screening & Macroscopic Analysis of Ficus dalhousiae Miq 7(1): January-March, 2015, 9-12, ISSN 0975-2331
  4. Research Journal of Pharmaceutical, Biological and Chemical Sciences Wound Healing Effect of Ficus Dalhousiae Miq Stem Bark Ethanolic Extract In Excision And Incision Wounded Wistar Rats 6(3), May – June 2015, 427, ISSN: 0975-8585
  5. International Current Pharmaceutical Journal Formulation of fast disintegrating domperidone tablets using Plantago ovata mucilage by 32 full factorial design.July 2015, 4(8): 415-419

Books:

Natural Product Chemistry-Career Publication (In press)

Area of Research Expertise: Phytochemistry, Analytical Method Development for quantification of phytoconstituents in polyherbal formulations.

Research Projects Handled:

  1. Effect of storage conditions on anti oxidant activities of some crude plant materials containing polyphenolic constituents (Minor Research Project grant from Mumbai University).
  2. Comparative analysis of total phenols and flavonoid content in different parts of Cissus quadrangularis (Minor Research Project grant from Mumbai University).
  3. Studies on Cissus quadrangularis (Ph. D Dissertation at Institute of Chemical Technology, Mumbai, grant from UGC, New Delhi)
  4. Analytical method development for quantification of phytoconstituents in polyherbal formulations (at Institute of Chemical Technology, Mumbai, sponsored by Nisarga Biotech Pvt. Ltd, Satara)

Research Publications:

  1. “Validated HPLC method development for simultaneous analysis of withaferin-A and 6- gingerol”, Acta Chromatographica, 22 (1), 2010, 151-57. (International) Impact factor 0.64
  2. Improved High-Performance Liquid Chromatography–DAD Method for the Simultaneous Analysis of Quercetin and Kaempferol in the Stems of Cissus quadrangularis Linn., Acta Chromatographica, 21 (1), 2009, 95–103. (International) Impact factor 0.64
  3. Effect of Storage Condition on Polyphenol Content of Emblica officinalis, Terminalia belerica And Terminalia chebula, American Journal of Pharmatech Research, 2016, 6(1), 313-324 (International).
  4. Novel validated HPLC method development for simultaneous analysis of curcumin and β-boswellic acid, American Journal of PharmTech Research, 2016; 6(2), 201-2018, ISSN: 2249-3387 (International).
  5. Simulaneous RP-HPLC analysis of Quercetin and Kaempferol in different plant part of Cissus quadrangularis, International Journal of Pharmacy and Pharamceutical Science, (Accepted and scheduled for publication, Vol. 8, Issue 7, July 2016, ISSN- 0975-1491).
  6. “Long chain aliphatic hydrocarbons from Cissus quadrangularis”, Indian Drugs, 47 (5), May 2010, 52-54.
  7. Lipid constituents from Cissus quadrangularis leaves”, Pharmacognosy Research Journal, Vol. 1, Issue 4, July-Aug 2009, 231-233.
  8. Phytochemical studies on Cissus quadrangularis Linn., Pharmacognosy Research Journal, Vol. 1, Issue 4, July-Aug 2009, 213-215.
  9. “In Vitro Regeneration Of Roots Of Phyla nodiflora And Leptadenia reticulata And Comparison Of Roots From Cultured And Natural Plants For Secondary Metabolites”, Indian Journal of Experimental Biology, Vol. 40, Dec 2002, 1382-1386. (Impact factor 1.195)
  10. Effect of Gibberellic acid on Coleus aromaticus Benth, Indian Drugs, 45 (3) March 2008, 213-214.
  11. Studies on mucilage of Orchis lattifolia Linn., Indian Drugs, 43 (4), 2006, 350-353.
  12. “In Vitro Free Radical Scavenging Activity of Lepidium sativum”, Plant Archives, Vol. 3 (2), Oct 2003, 315-318. (International)
  13. In Vitro Micropropagation of Rauwolfia serpentina Through Multiple Shoot Generation”, Ancient Science of Life, Vol 23 (1), July 2003, 44-49.
  14. “In Vitro Culture Studies for Callus and Root Generation of Boerhaavia diffusa” Ancient Science of Life, Vol. 22 (4), April 2003, 134-139.
  15. “Murraya koenigii: An updated review”, International Journal Of Ayurvedic and Herbal Medicine, 2 (4), 2012, 607-627. (International)
  16. “Nutritional Management for Pregnant Women- an extended role of Pharmacist”, Journal of Pharmacy Research, 5 (12), 2012, 5485-88.
  17. Anti Fertility Agents of Natural Origin- A Review”, Plant Archives, Vol. 4 (2), 223-233, Oct 2004. (International)
  18. “Jivanti: A Review”, The Indian Journal of Natural Product, Vol. 19(3), 11-15, 2003.
  19. “Coenzyme Q 10: A Review”, Ancient Science of Life, Vol. 22 (2), Oct 2002, 49-53.

Area of Research Expertise: LC-MS/MS and HPLC method development and validation

Research Projects Handled:

Minor Research Project

  1. Development and Validation of Stability Indicating HPLC Method for Simultaneous Estimation of Aspirin, Clopidogrel and Rosuvastatin
  2. Development and Validation of Stability Indicating HPLC Method for Simultaneous Estimation of N-Acetyl cysteine and Ambroxol hydrochloride
  3. UV spectrophotometric method for simultaneous estimation of Tramodol hydrochloride and Aceclofenac in bulk and tablet dosage form
  4. Absorption correction method for the simultaneous estimation of N-Acetyl cysteine and Ambroxol hydrochloride in bulk and tablet dosage form
  5. Simultaneous estimation of Nigella sativa seed oil and ginger extract in pharmaceutical dosage form by UV spectrophotometry
  6. Simultaneous UV spectrophotometric method for estimation of Albendazole and Levamisole hydrochloride in tablet dosage form

Guided Research project of M. Pharm. Students

  1. Stability indicating HPLC method for simultaneous estimation of Cefuroxime Axetil and Linezolid in Pharmaceutical Formulation
  2. Development and validation of stability indicating RP-HPLC method for simultaneous estimation of Aceclofenac and Paracetamol in Pharmaceutrical Formulation
  3. Development and validation of RP-HPLC method for simultaneous estimation of Albendazole and Levamisole hydrochloride in tablet dosage form
  4. Stability indicating RP-HPLC method development and validation for the simultaneous estimation of Tramodol hydrochloride and Aceclofenac in Pharmaceutical dosage form
  5. Development and validation of analytical method for the simultaneous estimation of Satranidazole and Mupirocin in Pharmaceutical dosage form

Research Publications:

  1. L. Jeeboi, S. Boddu, V. Panda, “A review on analytical methods for estimation of tramadol hydrochloricde”, AJPTR, vol.5, no.5,October 2015.[ISSN: 2249-3387]
  2. D. A. Jadhav, S. Boddu,S. Kadam, V. Kinjawadekar, “Simultaneous UV spectrophotometric method for estimation of Albendazole and Levamisole hydrochloride in tablet dosage form,”AJPTR,vol.5, no.5,October 2015..[ISSN: 2249-3387]
  3. Jeeboi, S Boddu,“UV spectrophotometric method for simultaneous estimation of Tramodol hydrochloride and Aceclofenac in bulk and tablet dosage form,” International Journal of Pharmacy and Pharmaceutical sciences ,vol.8 ,no.5,May 2016.[ISSN :0975-1491]
  4. V Kinjawadekar, S Boddu, D Jadhav, S Rathod, “Absorption correction method for the simultaneous estimation of N-Acetyl cysteine and Ambroxol hydrochloride in bulk and tablet dosage form”, International Journal of Pharmacy and Pharmaceutical sciences ,vol.8 ,no.5,May 2016.[ISSN :0975-1491]
  5. A. Jadhav, S. Boddu , “Development and validation of RP-HPLC method for simultaneous estimation of Albendazole and Levamisole hydrochloride in tablet dosage form”, Der Pharma Lettre,Vol.8,no.2,2016[ISSN:0975-5071]
  6. SnehalathaBoddu, MuniraMomin, Tejaswi Kale, Aditee Mishal, International Journal of Pharmaceutical Sciences and Research“Simultaneous estimation of Nigella sativa seed oil and ginger extract in pharmaceutical dosage form by UV spectrophotometry”, Vol 5(12), 2014,ISSN:5235-5239
  7. SnehalY.Kane, Snehalatha B, MuniraMomin, International journal of Chemical and analytical science, “ Simultaneous determination of Lansoprazole and Metronidazole in Pharmaceutical same dosage form by Reverse Phase-High Performance Liquid Chromatography”,Vol 5 Issue 2, 2014
  8. Snehalatha B, GowriSankar D, Asian Journal Of Pharmaceutical and Clinical Research Development and validation of LCMS/MS method for the estimation of Acrivastine in human plasma,Vol 7 Issue 4 ,2014
  9. DG Sankar, B Snehalatha, K Vijayasri, TK Murthy, JMR Kumar, M Reddy.Visible spectrophotometric Methods for the Determination of Venlafaxine Hydrochloride and Ritodrine Hydrochloride in Pharmaceutical Formulations Asian Journal of Chemistry Vol.15, No.1,2003
  10. DG Sankar, K Vijayasri, B Snehalatha, TK Murthy, JMR Kumar, M Reddy. Spectrophotometric estimation of Venlafaxine Hydrochloride and Ritodrine Hydrochloride,Asian Journal of Chemistry Vol.15, No.1,2003.
  11. DG Sankar, MV Krishna, N Sujatha, L Prasad, LA Rama, BS Latha.Development and Validation of RP-HPLC method for the estimation of Torasemide In Pure form And In Pharmaceutical Dosage Forms ,Analytical Chemistry ,Vol.3, Issue 4-6, 2007.

Books Published:

Patents:

rea of Research Expertise:

  1. Study of drug intermediate
  2. Synthesis of heterocyclic compounds and its Pharmacological Evaluation for antiepileptic, antihypertensive, anti-inflammatory etc.
  3. Optimization Techniques
  4. Isolation of Phytoconstituents from herbal Plant its derivatization and Pharmacological Evaluation.
  5. Phytochemical Studies of Natural Products.

Research Projects Handled:

  1. Study of drug intermediate (M.Pharm Thesis)

Minor Research Project of Mumbai University:

  1. Synthesis and Anticonvulsant activity of pyrazole-5-linked heterocyclics. Mumbai University Grant Received Research Project No 373 Ref No APD/237/345 of 2012 dated 17th November 2012.
  2. Synthesis and anti-inflammatory activity of substituted pyrazole-5-one. Mumbai University Grant Received Research Project No 321 Ref No APD/237/419 of 2016 dated 8th Feb. 2016.

Current Research Projects being handled: Isolation of reserpine from Rauwolfia Species its derivatization and Pharmacological Evaluation of analogues.

Research Publications:

  1. Amjad Ali M. Iqbal, Firoz A. Kalam Khan, Mohib Khan “Ethno-Phytopharmacological Overview on Rauwolfia tetraphylla Linn”, International Journal of Pharmaceutical & Phytopharmacological Research Vol. 2 (4) Jan-Feb 2013, 247-251.
  2. Amjad Ali M. Iqbal ,Firoz A. Kalam Khan, Imtiyaz Ansari, Altamash Quraishi,Mohib Khan ” Ethno-Phytopharmacological Overview on Rauwolfia densiflora (Wall) Benth.ex Hook.f” ” International Journal of Pharmaceutical & Phytopharmacological Research, 2013, 2(5): 372-376 .”
  3. Amjad Ali M. Iqbal ,Imtiyaz Ansari, Mohib Khan,”Comparative Pharmacognostical Evaluation of Roots of Four Rauwolfia Species”, International Journal of Pharmaceutical & Phytopharmacological Research, 2014;3(4):289-295
  4. Mohib Abdul Jalil Khan *, Imtiyaz Ansari, Amjad Ali Mohammad Iqbal” Isolation of volatile oil from culinary drugs and their antidepressant potential. Int J Adv Pharmacy Med Bioallied Sci. 3, 3, 2015.

Books Published:

Patents:

Area of Research Expertise: Design, synthesis and biological evaluation of metabolic pathway inhibitors of microorganisms.

Research Projects Handled: Design, synthesis and biological evaluation of metabolic pathway inhibitors of microorganisms. (PhD)

Research Publications:

  1. Manuscript entitled “Antifungal Activity And Synergy Studies Of Polysubstituted Alicyclic Analogues” Palsule Desai N H, Kakwani MD, Lele AC, Raju A, Degani MS, International Journal of Pharmaceutical research and Bioscience, 2014; Volume 3(4): 14-31 (Impact factor: 4.27)
  2. Manuscript entitled “Studies On 5-Cyanouracils: Expedient Synthetic Protocol For Synthesis Of Novel Pyrido[2,3-D]Pyrimidine And Pyrimido [4,5-D]Pyrimidine Analogs With Potential Pharmacological Activity” Yogesh Pedgaonkar, Arundhati Lele, Nutan H Palsule Desai, Mariam S Degani; Int J Pharm Bio Sci 2014 Oct; 5(4): (P) 422 – 439 (Impact factor:
  3. Manuscript entitled “Ultrasound Promoted Facile Synthesis of nitriles from aldehydes”, Arundhati Chandrashekhar Lele, Nutan Hanmant Palsule Desai, Mariam Sohel Degani; Journal of Pharmacy Research, Vol 8, No 7, (2014). (Impact factor:
  4. Manuscript entitled “Novel 4h-1,2,4-Triazol-3-yl Cycloalkanols As Potent Antitubercular Agents” Nutan H. Palsule Desai, Ranjeet Bairwa, Manoj Kakwani, Nilesh Tawari, M. K. Ray, M. G Rajan, Mariam Degani , Medicinal Chemistry Research, 22 (1), (2013), 401-408. DOI:10.1007/s00044-012-0043-9. (Impact factor:1.61)
  5. Manuscript entitled “A Single Step, Mild, Neutral, Catalyst Free Method for Cyanohydrin Synthesis” Mariam S. Degani, Manoj D. Kakwani, Nutan H Palsule Desai, RanjeetBairwa, Monatshefte fur Chemie, Springerlink, (2012) 143:461-465, DOI: 10.1007/s00706-011-0613-4. (Impact factor: 1.629)
  6. Manuscript entitled “Synthesis and preliminary biological evaluation of novel N-(3-aryl- 1,2,4-triazol-5-yl) cinnamamide derivatives as potential antimycobacterial agents: An operational Topliss Tree approach” Manoj D. Kakwani, Nutan H. Palsule Desai, Arundhati C. Lele, Muktikant Ray, M. G. R. Rajan, and Mariam S. Degani, Bioorganic Medicinal Chemistry Letters, 21 (2011) 6523–6526. Elsevier, DOI:10.1016/j.bmcl.2011.08.076. (Impact factor: 2.903)

Patents: Nil

Area of Research Expertise: CRDDS, NDDS, Topical dosage forms, Nanotechnology

Research Projects Handled:

Minor Research Project of Mumbai University

  1. Design and Evaluation of Castor oil based Anti-inflammatory Emulgel for Arthritis
  2. Solubility enhancement of poorly soluble drugs by employing solid dispersion technique

Guided Research project of M. Pharm. Students

  1. Formulation and development of NDDS using cyclodextrin
  2. Formulation and characterization of liposomes
  3. Formulation and characterization of liposomes
  4. Evaluation of controlled drug delivery systems
  5. Preparation and study of novel drug delivery system
  6. Preparation and evaluation of oral dosage formulation
  7. Studies in development of controlled drug delivery system
  8. Formulation and evaluation of controlled drug delivery system
  9. Formulation, development and evaluation of NDDS
  10. Design and development of oral drug formulation
  11. Optimization and evaluation of pharmaceutical dosage forms
  12. Design and development of drug delivery systems
  13. Design and development of novel drug delivery system
  14. Design, optimization and testing of oral delivery system
  15. Formulation and optimization of oral drug delivery system
  16. Formulation and development of novel drug delivery system
  17. Preparation and characterization of oral controlled drug delivery system
  18. Development and evaluation of novel drug delivery system
  19. Design and characterisation of dosage forms
  20. Preparation and evaluation of oral drug delivery system
  21. Formulation and evaluation of delivery systems

 

Research Publications:

  1. Sudha Rathod, Rasika K, Asish D,International Journal of Pharmacy and Pharmaceutical Sciences , “In Vitro released and in vivo tissue localization of 5-fluro Uracil loaded Microspheres” , International Journal of Pharmacy and Pharmaceutical Sciences, Vol 6 ,issue 1, 2014, ISSN- 0975-1491.
  2. Asmita Singh ,Sudha Rathod, International Journal of Pharm.Sciences and Research(IJPSR), “Design, Development and Characterization of Liposomal Neem Gel”, Vol 5 ,Issue.04 Apr 2014, ISSN:0975-9492.
  3. Rathod S.,Surve GD,Phansekar M, Bhagwan A, IJPRS , “A Review on Mouth Dissolving Film Technology”, Vol-3 I-1, 2014, ISSN No. 2277-7873.
  4. Sudha Rathod, Vishakha Kulkarni .IJAPR “Development and evaluation of curcumin Liposomal Gel” April 2013. Vol.4/ Issue 4, 1635-1639
  5. Sudha Rathod, Sadaf Momin .IJAPR “Development validation and stability study for simultaneous estimation of metformin and sitagliptin by hplc in bulk and marketed formulation”. May 2013 Vol.4/ Issue 4, 796-1802
  6. Sudha Rathod, S.G. Deshpande. “Patient Compliant ophthalmic Dosage form of Gatifloxacin”. IJPTR, Sept 2012, Vol 4, No. 3, ISSN 0974- 4304.
  7. Sudha Rathod, Vishakha Kulkarni, “Natural Polymers-A Comprehensive Review”. IJRPBS, Dec 2012, Vol.3, ISSN 2229-3701.
  8. Sudha Rathod, S.G. Deshpande. “Design and evaluation of Liposomic formulation of pilocarpine nitrate” Indian Journal of Pharm. Sci. March – April 2010, 72(2) : 155- 160.
  9. Sudha Rathod, S.G. Deshpande. “Bioavailability studies of ocular gels of Pilocarpine micropheres.” International Journal of Pharm. Tech Research, April – June 2010, 0974-4304Vol. 2, No2. PP 1022-1029.
  10. Sudha Rathod, S.G. Deshpande. “Design and Evaluation of Drug Loaded Erythrocytes.” International Journal of Pharm. Tech Research, April – June 2010, 0974-4304. Vol.2, No.2, PP 1550 – 1557.
  11. Sudha Rathod and S.G. Deshpande. Albumin microspheres as an ocular Delivery systemfor pilocarpine nitrate, Indian Journal of Pharm. Sci. Vol. 70, Issue (2) PP 193-197 March– April 2008.

 

Books Published:

Patents:

  1. Indian patent (MUM/2384/2014): Castor oil emulgel

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